off his meds (11. 443)

Via TYWKIWBI (indeed), we learn that Dr Lecter’s famously creepy quip from Silence of the Lambs, the psychiatrist turned cannibalistic serial killer consulted for insight to help catch another, “A census taker once tried to test me—I ate his liver with some fava beans and nice Chianti” is more than a memorable quote but also a subtle joking admission that he’s not presently adhering to his prescribed pharmacological regimen. The fictional doctor’s most aberrant tendencies could be managed with a class of drugs called monoamine oxidase inhibitors (a rather blunt instrument from the 1950s used to treat a whole range of disorders with various levels of success), which Lecter would of course know as well as the contraindication of this particular repast, all noted for having high levels of tyramine (as well as blue cheese) and could cause dangerous side-effects—the kind of adverse chemical reactions that the poor grapefruit usually gets blame for. In the novel by Thomas Harris that the 1991 film is adapted from, mostly faithfully, the better-paired wine is Amarone is mentioned but was presumably substituted for cadence in delivery by Anthony Hopkins and as something audiences would be more familiar with.